Ischemic Tolerance Induced by Cerebral Preconditioning: New Urologic Research Area
نویسندگان
چکیده
منابع مشابه
Ischemic Tolerance Induced by Cerebral Preconditioning: New Urologic Research Area
Voiding function and dysfunction, bladder physiology and pharmacology covering peripheral and central nerve system (CNS) have been given much attention during the last decades as confirmed by countless researches and clinical articles. In contrast, cerebral preconditioning and associated brain lesions in urologic field generated only a few clinical articles regarding to ischemic stroke [1,2]. T...
متن کاملHypoxic Preconditioning-Induced Cerebral Ischemic Tolerance
Background and Purpose—The importance of bioactive lipid signaling under physiological and pathophysiological conditions is progressively becoming recognized. The disparate distribution of sphingosine kinase (SphK) isoform activity in normal and ischemic brain, particularly the large excess of SphK2 in cerebral microvascular endothelial cells, suggests potentially unique celland region-specific...
متن کاملMechanisms and Prospects of Ischemic Tolerance Induced by Cerebral Preconditioning
In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance. The purpose of this review is to summarize the current state of knowledge about mechanisms and potential applications of cerebral preconditioning and ischemic tolerance. Articles related t...
متن کاملEndogenous Agmatine Induced by Ischemic Preconditioning Regulates Ischemic Tolerance Following Cerebral Ischemia
Ischemic preconditioning (IP) is one of the most important endogenous mechanisms that protect the cells against ischemia-reperfusion (I/R) injury. However, the exact molecular mechanisms remain unclear. In this study, we showed that changes in the level of agmatine were correlated with ischemic tolerance. Changes in brain edema, infarct volume, level of agmatine, and expression of arginine deca...
متن کاملSarcosine preconditioning induces ischemic tolerance against global cerebral ischemia.
Brain ischemic tolerance is an endogenous protective mechanism activated by a preconditioning stimulus that is closely related to N-methyl-d-aspartate receptor (NMDAR). Glycine transporter type 1 (GlyT-1) inhibitors potentiate NMDAR and suggest an alternative strategy for brain preconditioning. The aim of this work was to evaluate the effects of brain preconditioning induced by sarcosine, a Gly...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Neurourology Journal
سال: 2010
ISSN: 2093-6931
DOI: 10.5213/inj.2010.14.4.201